Effects of long-term administration of various dietary prebiotic supplements on the growth, immune cell activity and digestive tract histology of juvenile vimba <i>(Vimba vimba)</i>

Abstract Introduction The experiment was set to determine the effects of long-term (55-day) use three commercial prebiotics including Saccharomyces cerevisiae –derived β-glucans and one inulin on juvenile vimba (Vimba vimba) reared intensively under controlled conditions. Material Methods Six-month-old fish were fed feed (Control group, n = 90), or same supplemented with 0.02% Leiber Beta-S (BS 0.20% Biolex MB40 (MB 0.30% CeFi (CE 90) 1.00% Orafti GR (IN for 55 days. Results In BS final growth parameters significantly lower than in Control while conversion ratio higher. No significant differences found between any other group respective parameters. respiratory burst activity head-kidney phagocytes all groups prebiotic-supplemented diets compared group. proliferative response lymphocytes stimulated by concanavalin A this not affected. histopathological analyses digestive tract, liver pancreas. Conclusion supplementation can negatively influence growth, conversion, nonspecific cellular resistance T juveniles.